Table 2.

Examination schedule for a 26-week toxicity study of chronic sargramostim inhalation

Item	Frequency and timing of examination
General condition	Twice daily
Food uptake	Once daily
Body weight	Once weekly
Heart rate/min	Pre- and post-inhalation at day 1, week 13 and 25
Blood pressure	Pre- and post-inhalation at day 1, week 13 and 25
Electrocardiogram	Pre- and post-inhalation at day 1, week 13 and 25
Ophthalmology test	Pre-inhalation and week 13 and 25
Hematological test	Day -3, 8, 92, and 176
Clinical chemistry	Day -3, 8, 92, and 176
Urinalysis	Weeks -1, 13, and 25
Autopsy	Week 27