Table 2.

The association between PA total MET and 6 thyroid hormone indexes in the whole population by linear regression analyses (n=2118).

dependent variable	independent variable	crude model		adjusted model 1		adjusted model 2		adjusted model 3
TT4RI	PAMET	95%CI	P	95%CI	P	95%CI	P	95%CI	P
	Q1	ref		ref		ref		ref
	Q2	-0.241(-2.846, 2.363)	0.851	0.147(-2.370, 2.663)	0.905	0.117(-2.493, 2.727)	0.925	0.000(-3.269, 3.268)	1.000
	Q3	-3.757(-6.322, -1.191)	0.005	-2.736(-5.170, -0.302)	0.029	-2.551(-5.101, -0.002)	0.05	-2.598(-5.800, 0.604)	0.091
	P for trend		0.005		0.027		0.046		0.08
TSHI	Q1	ref		ref		ref		ref
	Q2	-0.081(-0.158, -0.003)	0.041	-0.078(-0.153, -0.003)	0.042	-0.067(-0.146, 0.011)	0.088	-0.075(-0.166, 0.016)	0.087
	Q3	-0.195(-0.300, -0.089)	<0.001	-0.177(-0.292, -0.061)	0.004	-0.167(-0.287, -0.046)	0.010	-0.169(-0.320, -0.019)	0.034
	P for trend		<0.001		0.004		0.009		0.027
TFQI	Q1	ref		ref		ref		ref
	Q2	-0.039(-0.084, 0.006)	0.09	-0.033(-0.075, 0.009)	0.121	-0.033(-0.076, 0.009)	0.115	-0.034(-0.084, 0.016)	0.145
	Q3	-0.108(-0.152, -0.064)	<0.001	-0.096(-0.142, -0.051)	<0.001	-0.093(-0.140, -0.046)	<0.001	-0.088(-0.147, -0.029)	0.012
	P for trend		<0.001		<0.001		<0.001		0.009
TSH	Q1	ref		ref		ref		ref
	Q2	0.234(-0.336,0.803)	0.409	0.291(-0.350, 0.932)	0.358	0.271(-0.351, 0.893)	0.367	0.261(-0.497, 1.019)	0.416
	Q3	-0.179(-0.456,0.099)	0.199	-0.025(-0.349, 0.300)	0.876	0.011(-0.349, 0.371)	0.947	-0.011(-0.420, 0.398)	0.948
	P for trend		0.193		0.848		0.959		0.932
FT3	Q1	ref		ref		ref		ref
	Q2	0.047(-0.008,0.102)	0.089	-0.021(-0.074, 0.032)	0.414	-0.005(-0.059, 0.050)	0.858	-0.008(-0.071, 0.055)	0.757
	Q3	0.135(0.083,0.187)	<0.001	0.006(-0.045, 0.056)	0.82	0.009(-0.044, 0.062)	0.716	0.008(-0.055, 0.071)	0.751
	P for trend		<0.001		0.805		0.712		0.744
FT4	Q1	ref		ref		ref		ref
	Q2	-0.208(-0.513, 0.096)	0.173	-0.152(-0.436, 0.132)	0.281	-0.154(-0.432, 0.124)	0.256	-0.144(-0.478, 0.190)	0.318
	Q3	-0.636(-0.902, -0.370)	<0.001	-0.542(-0.779, -0.305)	<0.001	-0.544(-0.786, -0.302)	<0.001	-0.492(-0.803, -0.181)	0.010
	P for trend		<0.001		<0.001		<0.001		0.007

adjusted 1: adjusted for age, race, sex.

adjusted 2: adjusted for age, race, sex, marital status, education level, family annual income, BMI.

adjusted 3: adjusted for age, race, sex, marital status, education level, family annual income, BMI, Hypertension, stroke, diabetes, smoke, alcohol using.

PA, Physical activity; TT4RI, Thyrotroph Thyroxine Resistance Index; TSHI, Thyroid Stimulating Hormone Index; TFQI, Thyroid Feedback Quantile-based Index; TSH, Thyroid Stimulating Hormone; FT3, Free triiodothyronine; FT4, Free Thyroxine.