Figure 7.

Tacrolimus exposure parameters stratified by age group. (a) Tacrolimus trough levels, (b) tacrolimus intrapatient variability (TacIPV) quantified by coefficient of variation (CV) and mean absolute deviation (MAD), (c) concentration/dose ratio (C/D ratio) corrected for body surface area (BSA), (d) C/D ratio corrected for body weight (BW), (e) C/D ratio corrected for BSA scaled for 1.73 m² stratified by age and time period posttransplant. Color coding represents different age groups. Benjamini-Hochberg-corrected statistical significance values are indicated by asterisks as follows: ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.