Table 2.

IMPACT CKD key model outputs

Domain	Output
Clinical impact	Percent changes in CKD subpopulations.
	Number of patients with CKD by stage.
	Prevalence of CKD by stage.
	Number of patients with comorbidities (e.g., diabetes, hypertension, heart failure).
	Proportion of diagnosed and undiagnosed patients with CKD.
	Number of patients undergoing dialysis.
	Number of patients undergoing transplant.
	Annualized cardiovascular cases by CKD stage (i.e., myocardial infarction, stroke, hospitalization due to heart failure).
	Total cardiovascular cases by type of CVD.
	Annualized AKI cases by CKD stage.
	Annual mortality by CKD stage.
Health care resource use	Number of ER visits in patients with CKD-by-CKD stage, and RRT status.
	Number of hospitalizations in patients with CKD-by-CKD stage, and RRT status.
	Number of critical care visits in patients with CKD-by-CKD stage, and RRT status.
	Number of outpatient visits in patients with CKD-by-CKD stage, and RRT status.
Economic impact	Costs associated with diagnosed CKD, dialysis, and transplant by CKD stage.
	Costs associated with clinical events.
Patient impact	QALYs (patient relevant preference management) per patient with CKD.
	Financial well-being (using CFPB scores) and financial burden (using FACIT-Cost score) of diagnosed patients with CKD and patients without CKD.
	Cumulative lost income for patients with CKD and caregivers by CKD stage, and RRT status.
Societal impact	Cumulative missed workdays for patients with diagnosed CKD and caregivers by CKD stage, and RRT status.
	Cumulative lost GDP for patients with diagnosed CKD and caregivers by patient presenteeism/absenteeism, caregiver absenteeism.
	Cumulative lost FTEs for patients with diagnosed CKD and caregivers by patient presenteeism/absenteeism, caregiver absenteeism.
Environmental impact	Freshwater consumption among patients with diagnosed CKD by CKD stage, and RRT status.
	Fossil fuel depletion among patients with diagnosed CKD by CKD stage, and RRT status.
	Carbon production among patients with diagnosed CKD by CKD stage, and RRT status.

AKI, acute kidney injury; CKD, chronic kidney disease; CFPB, Consumer Financial Protection Bureau; CVD, cardiovascular disease; ER, emergency room; FACIT, Functional Assessment of Chronic Illness Therapy; FTE, full-time equivalent; GDP, gross domestic product; RRT, renal replacement therapy; QALY, quality-adjusted life year.