. Author manuscript; available in PMC: 2024 Nov 11.

Published in final edited form as: Ophthalmology. 2013 Jan 16;120(4):844–851. doi: 10.1016/j.ophtha.2012.10.036

Table 2.

Proposed AMD Clinical Classification

Classification of AMD	Definition (lesions assessed within 2 disc diameters of fovea in either eye)
No apparent aging changes	No drusen and No AMD pigmentary abnormalities^*
Normal aging changes	Only drupelets (small drusen ≤63 μm) and No AMD pigmentary abnormalities^*
Early AMD	Medium drusen >63 μm and ≤125 μm and No AMD pigmentary abnormalities^*
Intermediate AMD	Large drusen > 125 μm and/or Any AMD pigmentary abnormalities^*
Late AMD	Neovascular AMD and/or Any geographic atrophy

AMD = age-related macular degeneration.

AMD pigmentary abnormalities = any definite hyper- or hypopigmentary abnormalities associated with medium or large drusen but not associated with known disease entities.