Table.
No. of Surviving AREDS Participants | AREDS Participants Active in the Follow-up Study, % | P Valueb | |
---|---|---|---|
All | 4203 | 84.4 | |
AMD category | |||
1 | 1031 | 88.5 | <.001 |
2 | 960 | 85.8 | |
3 | 1435 | 83.8 | |
4 | 777 | 78.6 | |
AREDS treatment assignment | |||
Placebo | 1312 | 83.8 | .61 |
Antioxidants | 1301 | 85.3 | |
Zinc | 806 | 83.5 | |
Antioxidants plus zinc | 784 | 84.9 | |
Age, y | |||
<65 | 957 | 90.4 | <.001 |
65–69 | 1432 | 87.6 | |
≥70 | 1814 | 78.8 | |
Sex | |||
Female | 2412 | 84.2 | .69 |
Male | 1791 | 84.7 | |
Educational levelc | |||
High school or less | 1460 | 80.7 | <.001 |
Some college | 1285 | 83.7 | |
College graduate | 1455 | 88.8 | |
Race | |||
Nonwhite | 179 | 77.1 | .006 |
White | 4024 | 84.8 | |
Smoking status | |||
Never | 1931 | 87.1 | <.001 |
Former | 1974 | 83.2 | |
Current | 298 | 75.5 | |
BMId | |||
<24.9 | 1369 | 85.1 | .08 |
25.0–29.9 | 1761 | 85.2 | |
≥30.0 | 1071 | 82.3 | |
Hypertension | |||
Normal | 2611 | 86.6 | |
Controlled | 993 | 82.0 | <.001 |
Uncontrolled and treated | 280 | 76.8 | |
Uncontrolled and untreated | 319 | 81.5 | |
Angina | |||
No | 3802 | 84.8 | .07 |
Yes | 401 | 81.3 | |
Diabetes mellitus | |||
No | 3886 | 84.8 | .007 |
Yes | 317 | 81.3 |
Abbreviations: AMD, age-related macular degeneration; AREDS, Age-Related Eye Disease Study; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared).
Of the original 4757 AREDS participants enrolled in the controlled clinical trial (1992–2001), 554 (11.6%) died at the end of the clinical trial, with 4203 surviving at the beginning of the follow-up study (October 1, 2001).
Calculated by the χ2 test.
Three partipants were missing data.
Two participants were missing data.