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. 2024 Dec 25;13(4):99070. doi: 10.5501/wjv.v13.i4.99070

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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Possible mechanisms of interaction between periodontitis and coronavirus disease 2019 infection. (1) Periodontal pocket act like a reservoir for severe acute respiratory syndrome coronavirus 2 and an entrance into the blood stream; (2) Periodontitis as a source for increased direct inoculation of periodontopathic bacteria into the respiratory system in coronavirus disease 2019 (COVID-19) patients; and (3) Periodontitis as a source for increased systemic inflammation and priming the immune system in COVID-19 patients. (Created at BioRender.com)