Table 2.
Multivariable analyses in the 1762 patients with complete data for the 6 prognostic covariates in the training data set
| Covariates | Regression coefficient | HR (95% CI) | P value |
|---|---|---|---|
| Multivariable Cox analyses | |||
| Male | 0.2026 | 1.2 (1.0-1.5) | .02 |
| Age/100, y | 1.5668 | 4.8 (2.3-9.8) | <.001 |
| (Hemoglobin/100)−2, g/L | 0.3108 | 1.4 (1.3-1.5) | <.001 |
| Blood blasts, % | 0.1085 | 1.1 (1.1-1.2) | <.001 |
| Spleen size, cm below costal margin | 0.0675 | 1.1 (1.0-1.1) | <.001 |
| High-risk ACAs in Ph+ cells∗ | 0.5458 | 1.7 (1.1-2.8) | .03 |
| Multivariable Fine-Gray analyses | |||
| Male | 0.1919 | 1.2 (1.0-1.5) | .01 |
| Age/100, y | 1.6160 | 5.0 (2.5-10.3) | <.001 |
| (Hemoglobin/100)−2, g/L | 0.3105 | 1.4 (1.2-1.5) | <.001 |
| Blood blasts, % | 0.1087 | 1.1 (1.1-1.2) | <.001 |
| Spleen size, cm below costal margin | 0.0671 | 1.1 (1.0-1.1) | <.001 |
| High-risk ACAs in Ph+ cells∗ | 0.5461 | 1.7 (1.1-2.8) | .02 |
HR, hazard ratio; N, no; Y, yes.
∗
High-risk ACAs in Ph+ cells were scored as categorical covariates (“Y/N”) in the regression models.