Table 2. Average Number of Contacts between Each Lipid Component of the VL Mixture and (i) the Chemically Modified Residue in the Antibody, In the Three Replicas Considered Per System, Or Contacts between Each Lipid Component and (ii) Lin3 or Fus4 Free Molecules in Simulations Where 25 of Them Were Present, and the Maximum Number of Molecules Binding Each Lipid on a Per Frame Basis Was Averaged. The Composition of the VL Bilayer Used Is Indicated in the First and Second Columns.
Lipid | Mol% | (i) Lin3 | (i) Fus4 | (ii) Lin3 | (ii) Fus4 |
---|---|---|---|---|---|
POPS | 7 | 0.0 ± 0.0 | 0.0 ± 0.1 | 2.2 ± 0.7 | 1.7 ± 0.6 |
SPM | 17 | 0.7 ± 0.4 | 0.4 ± 0.5 | 2.6 ± 0.6 | 2.4 ± 0.6 |
Chol | 46 | 2.3 ± 0.7 | 2.5 ± 0.9 | 4.2 ± 1.0 | 3.7 ± 0.7 |
POPC | 14 | 0.2 ± 0.4 | 0.1 ± 0.3 | 3.5 ± 0.8 | 2.4 ± 0.5 |
POPE | 16 | 2.1 ± 0.3 | 1.8 ± 0.5 | 3.3 ± 0.8 | 2.6 ± 0.6 |