Table 2.
Significantly enriched GO terms within differentially expressed transcript and protein data. Terms enriched at FDR < 0.05, after manual curation to remove redundancies, retaining the terms with lowest FDR. Ontology groups are Molecular Function (MF), Biological Process (BP) and Cell Compartment (CC). Full lists of enriched terms are in Supplementary Material 6
| GO Category | Term | Ontology group | No. genes in DE set | P value | FDR |
|---|---|---|---|---|---|
| Whole body RNA | |||||
| VIR parent up | |||||
| 0004177 | aminopeptidase activity | MF | 8 | 2.72E-06 | 0.0270 |
| AVR parent up | |||||
| 0004177 | aminopeptidase activity | MF | 9 | 1.43E-07 | 0.0014 |
| 0017177 | glucosidase II complex | CC | 4 | 2.09E-06 | 0.0104 |
| AVR F1 up | |||||
| 0017177 | glucosidase II complex | CC | 3 | 2.42E-06 | 0.0240 |
| VIR F1 up | No terms | ||||
| Heads RNA | |||||
| VIR up on R host | |||||
| 0045271 | respiratory chain complex I | CC | 11 | 1.55E-07 | 9.63E-05 |
| 0005743 | mitochondrial inner membrane | CC | 22 | 2.01E-07 | 0.0001 |
| 0004177 | aminopeptidase activity | MF | 10 | 2.13E-06 | 0.0009 |
| 0016491 | oxidoreductase activity | MF | 31 | 3.24E-06 | 0.0012 |
| 0005875 | microtubule associated complex | CC | 25 | 1.72E-05 | 0.0052 |
| 0019395 | fatty acid oxidation | BP | 5 | 2.44E-05 | 0.0064 |
| 0042826 | histone deacetylase binding | MF | 4 | 0.00011 | 0.0275 |
| 0045239 | tricarboxylic acid cycle enzyme complex | CC | 3 | 0.00014 | 0.0327 |
| 0004448 | isocitrate dehydrogenase activity | MF | 3 | 0.00015 | 0.0338 |
| VIR up on S host | |||||
| 0006635 | fatty acid beta-oxidation | BP | 5 | 1.05E-06 | 0.0082 |
| 0004177 | aminopeptidase activity | MF | 9 | 2.66E-06 | 0.0082 |
| 0004449 | isocitrate dehydrogenase (NAD +) activity | MF | 3 | 1.40E-05 | 0.0198 |
| 0006099 | tricarboxylic acid cycle | BP | 6 | 3.54E-05 | 0.0389 |
| AVR up on R host | |||||
| 0004177 | aminopeptidase activity | MF | 10 | 7.77E-07 | 0.00771 |
| AVR up on S host | |||||
| 0004177 | aminopeptidase activity | MF | 11 | 5.59E-09 | 5.53E-05 |
| Salivary gland proteins | |||||
| VIR up | |||||
| 0003983 | UTP:glucose-1-phosphate uridylyltransferase activity | MF | 3 | 4.97E-06 | 0.0213 |
| AVR up | No terms | ||||