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. 2024 Nov 6;20:2827–2833. doi: 10.3762/bjoc.20.238

Table 2.

Addition reaction using other N,O-acetals 1 and alkynes 3.

graphic file with name Beilstein_J_Org_Chem-20-2827-i002.jpg

entry R1 compound R2 compound product yield, %

1 p-MeC6H4 1a Bu 3b 4b 58
2 p-MeC6H4 1a t-Bu 3c 4c 55
3 p-MeC6H4 1a Me3Si 3d 4d 69
4 Et 1b Ph 3a 4e 72