Table 3. Cox regression analysis comparing all-cause mortality after-propensity-score matching.

Variable	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value	HR (95% CHR)	P value
Age	1.02 (1.01 to 1.03)	<0.001	1.02 (1.01 to 1.03)	<0.001
Sex	1.00 (0.85 to 1.19)	0.96	0.87 (0.73 to 1.04)	0.125
Metastatic disease	1.24 (1.04 to 1.48)	0.017	1.24 (1.04 to 1.48)	0.018
ICI type	0.99 (0.95 to 1.02)	0.49	0.96 (0.93 to 1.00)	0.045
BMI≥25	0.71 (0.60 to 0.84)	<0.001	0.71 (0.60 to 0.84)	<0.001
T2DM	1.71 (1.20 to 2.43)	0.003	1.58 (1.08 to 2.31)	0.019
Hypertension	1.26 (1.05 to 1.51)	0.011	0.91 (0.73 to 1.14)	0.42
Heart failure	2.10 (1.45 to 3.04)	<0.001	1.30 (0.85 to 1.98)	0.22
Hyperlipidemia	1.13 (0.93 to 1.37)	0.21	0.85 (0.68 to 1.07)	0.162
Chronic kidney disease	2.00 (1.41 to 2.85)	<0.001	1.35 (0.91 to 1.99)	0.135
COPD	1.27 (0.85 to 1.90)	0.24	1.05 (0.69 to 1.60)	0.81
Ischemic heart disease	0.76 (0.19 to 3.06)	0.70	0.52 (0.12 to 2.20)	0.37

BMI unit: kg/m2.

COPD, chronic obstructive pulmonary disease; ICI, immune checkpoint inhibitorT2DM, type 2 diabetes mellitus