Chart 8.1. Types, doses, and routes of administration of estrogens and progestogens used in menopausal hormone therapy. MHT: menopausal hormone therapy.
TYPES, DOSES, AND ROUTES OF ADMINISTRATION OF ESTROGENS USED IN MHT | |
---|---|
Oral route | |
17-β-estradiol | 0.5, 1.0, 2.0 mg/day |
Estradiol valerate | 1.0 - 2.0 mg/day |
Transdermal route | |
17-β-estradiol - gel | 0.5, 0.75, 1.0, 1.5-3.0 mg/day |
17-β-estradiol - patch | 25, 50 mcg/day |
Vaginal route | |
Estriol cream | 1.0 mg/g |
Estradiol | 10 mcg per pill |
Promestriene | 10 mg/g |
TYPES, DOSES, AND ROUTES OF ADMINISTRATION OF PROGESTOGENS USED IN MHT | |
Oral route | |
Medroxyprogesterone acetate | 2.5 - 10.0 mg/day |
Cyproterone acetate | 1.0 - 2.0 mg/day |
Norethisterone acetate | 0.1 - 1.0 mg/day |
Nomegestrol acetate | 2.5 - 5.0 mg/day |
Dydrogesterone | 5.0 - 10.0 mg/day |
Drospirenone | 2.0 mg/day |
Micronized progesterone | 100 - 200 mg/day |
Transdermal route | |
Norethisterone acetate | 140 - 170 mcg/day |
Vaginal route | |
Micronized progesterone – soft gelatin capsules | 100 - 200 mg/day |
Intrauterine route | |
HIUD-levonorgestrel | 20 mcg/day |