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. 2024 Oct 15;46:e-rbgo100. doi: 10.61622/rbgo/2024rbgo100

Chart 8.1. Types, doses, and routes of administration of estrogens and progestogens used in menopausal hormone therapy. MHT: menopausal hormone therapy.

TYPES, DOSES, AND ROUTES OF ADMINISTRATION OF ESTROGENS USED IN MHT
Oral route  
17-β-estradiol 0.5, 1.0, 2.0 mg/day
Estradiol valerate 1.0 - 2.0 mg/day
Transdermal route  
17-β-estradiol - gel 0.5, 0.75, 1.0, 1.5-3.0 mg/day
17-β-estradiol - patch 25, 50 mcg/day
Vaginal route  
Estriol cream 1.0 mg/g
Estradiol 10 mcg per pill
Promestriene 10 mg/g
TYPES, DOSES, AND ROUTES OF ADMINISTRATION OF PROGESTOGENS USED IN MHT
Oral route  
Medroxyprogesterone acetate 2.5 - 10.0 mg/day
Cyproterone acetate 1.0 - 2.0 mg/day
Norethisterone acetate 0.1 - 1.0 mg/day
Nomegestrol acetate 2.5 - 5.0 mg/day
Dydrogesterone 5.0 - 10.0 mg/day
Drospirenone 2.0 mg/day
Micronized progesterone 100 - 200 mg/day
Transdermal route  
Norethisterone acetate 140 - 170 mcg/day
Vaginal route  
Micronized progesterone – soft gelatin capsules 100 - 200 mg/day
Intrauterine route  
HIUD-levonorgestrel 20 mcg/day