Table 3.

Population of Tax-specific cytotoxic T cells, Tax-expressed HTLV-1-infected cells, and IFN-γ production CD8+ T cells in RD participants who showed invalid T-SPOT.TB^® assay results.

Case	PVL (copies/100 PBMCs)	Tax tetramer+ T cells in CD8+ T cells (%)	Tax+ T cells in CD4+ T cells (%)			IFN-γ+ T cells in CD8+ T-cells (%)
			Whole cells	CD8-depleted PBMCs	Fold change	Whole cells	CD4-depleted PBMCs	Fold change
RD2	9.01	21.4	1.06	3.85	3.63	4.14	0.22	0.05
RD1	19.1	18.2	3.63	7.06	1.94	7.26	0.22	0.03
RD4	3.59	11.4	0.16	4.13	25.8	2.76	0.11	0.04
RD5	6.14	5.10	10.3	9.96	0.97	2.73	0.54	0.20
RD3	8.32	4.73	13.6	8.62	0.63	2.15	0.06	0.03

RD, rheumatic disease; PVL, proviral load; PBMCs, peripheral blood mononuclear cells.