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(A) Dose–response curve by measuring a K1-70 dilution series with the Turbo™ TBI bioassay (IC50 = 1.55 ng/mL, log (IC50) = 0.19; IC80 = 3.48 ng/mL, log (IC80) = 0.54). (B) Dose–response curve by measuring a K1-70 dilution series with the Thyretain® TBI bioassay (IC50 = 6.76 ng/mL, log (IC50) = 0.83; IC80 = 18.45 ng/mL, log (IC80) = 1.27).
