Table 1.
Contributions of the Research Topic.
| Title | Authors | Setting | Patients | Results |
|---|---|---|---|---|
| No causal relationship between serum vitamin D levels and alcoholic liver disease: a two-sample bidirectional Mendelian randomization study | Wu H, Wu L, Zhang Q, Li C, Li HY, Zhang BF. | Alcoholic liver disease (ALD) | Adults | No reciprocal causal link between serum VD and ALD susceptibility |
| Vitamin D in tuberous sclerosis complex-associated tumors | Tatsuro Nobutoki | Tuberous sclerosis complex-associated tumors |
Children | Review discussing the possible role of 1,25VD in pediatric tuberous sclerosis complex-associated tumors, and the significance of vitamin D signaling as adjuvant or alternative drug target |
| Vitamin D status, vitamin D receptor, CYP2R1, and CYP24A1 profiles in children | Iriani A, Rachman A, Fatina MK, Gemilang RK, Trisnandi A, Muskananfola FV, Nugraha MFI. | Vitamin D status | Children | VD level is reduced by aging in children; VDR level is also found different based on VD status |
| Explorative case control study on the associations of serum vitamin D3, folic acid and vitamin B12 levels on Kawasaki disease and coronary artery lesions | Chen Y, Liu X, Li B, Li J, Meng L, Ye C, Han L, Li H, Deng LL, Su Z, Zhang X. | Kawasaki disease and coronary artery lesions |
Children | Folic acid and VD3 were significantly reduced in children with KD, especially in those with coronary artery lesions |
| Changes in vitamin D status among adults from the COVID-19 pandemic to post-pandemic normality | Chen Y, Kong G. | COVID-19 | Adults | COVID-19 pandemic significantly impacted VD status, leading to an increased prevalence of deficiency, especially among males |
| Nonlinear correlation and mediation effects between serum 25-hydroxyvitamin D levels and all-cause mortality in COPD patients | Jiang Q, Jiang Y, Ma Z, Huang J, Li Y. | COPD | Adults | High prevalence of low VD in COPD patients; non-linear association between serum 25(OH)D concentration and all-cause mortality (better survival above 63.40 nmol/L), with VD mediating role between dietary inflammation and mortality (mediation analysis) |
| The effects of vitamin D supplementation on serum lipid profiles in people with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials | Lu Q, Liang Q, Xi Y. | Type 2 diabetes | Adults | The meta-analysis evidenced the benefit of VD supplementation in improving serum HDL and TG but not in LDL and TC levels |
| Associations of vitamin D status with all-cause and cause-specific mortality in long-term prescription opioid users | Dai S, Wu J, Wang P, Hu Z. | Opioid users | Adults | Non-linear association between serum 25(OH)D concentration and all-cause mortality |
| Implications of vitamin D levels or status for mortality in rheumatoid arthritis: analysis of 2001-2018 data from the National Health and Nutrition Examination Survey | Feng Y, Zhu P, Dandan Y, Wang X, Chen C, Zhang Z, Tian Y, Wang J, Liu S, Li J, Meng D, Wang K. | Rheumatoid arthritis (RA) | Adults | A significant negative correlation between 25(OH)D levels and overall mortality in individuals with RA, especially for mortality related to heart disease and cancer |
| Serum 25-hydroxyvitamin D concentrations and their impact on all-cause mortality in Parkinson's disease: insights from National Health and Nutrition Examination Survey 1999–2020 data | Yong Y, Dong H, Zhou Z, Zhu Y, Gu M, Li W. | Parkinson's disease | Adults | Non-linear association between serum 25(OH)D concentration and all-cause mortality (optimal survival rates at 75–100 nmol/L) |
| The complex relationship between vitamin D and kidney stones: balance, risks, and prevention strategies | Zhang F, Li W. | Kidney stones | Adults | The review discusses actual evidence on the relationship between vitamin D status and kidney stone risk, and the role of vitamin D supplementation for preventing and treating kidney stones. |
| Factors associated with vitamin D deficiency in health care workers exposed to SARS-CoV-2: a cross-sectional study | Villasis-Keever MA, Zurita-Cruz JN, Garduño-Espinosa J, López-Alarcón M, Barradas Vázquez AS, Miranda-Novales MG, Parra-Ortega I, López-Martinez B, García H, Klünder-Klünder M. | COVID-19 | Adults | High prevalence of VD deficiency in Mexican health care workers exposed to SARS-CoV-2, related to both personal health factors and occupational low VD values is high among health care workers, and TD2 was a significant risk factor associated with these values. conditions (e.g. T2D) |
| The relationship between physical activity levels and serum vitamin D levels varies among children and adolescents in different age groups | Ouyang S, Li Q, Liu Z, Yin Y. | Physical activity (PA) | Children and adolescents | PA and VD varies according to sex and age, with sun exposure level and BMI affecting PA/VD relationship |
| Comparative Analysis of COVID-19 Responses in Japan and Africa: Diet, Phytochemicals, Vitamin D, and Gut Microbiota in Reducing Mortality -A Systematic Review and Meta-Analysis | Santa K, Tamaki R, Watanabe K, Nagaoka I. | COVID-19 | Adults | Blood vitamin D levels are associated with COVID-19 mortality |
| Vitamin D Deficiency in Non-scarring and Scarring Alopecias: A Systematic Review and Meta-Analysis | Yongpisarn T, Tejapira K, Kunlawat Thadanipon K, Suchonwanit P. | Alopecias | Adults | Patients with non-scarring alopecia have insufficient serum VD level and increased incidence of vitamin D deficiency |
| Cardiometabolic factors and vitamin D deficiency in pediatric patients with chronic kidney disease | Fayoumi T, Gari A, Alarawi M, Almutairi S, Shalabi BH, Safdar O, Al Kadi H. | Chronic kidney disease (CKD) |
Children | Children with CKD and low VD ( ≤ 41.9 nmol/L) presented a more adverse cardiometabolic risk profile |
| Relationship between Serum Vitamin D Levels and the Atherogenic Index of Plasma (AIP): A Study Based on NHANES Database 2011–2018 | Hu T, Zhang Y, Chen Z, Su J. | Risk of atherosclerosis | Adults | A significant negative correlation and saturation effect was found between serum vitamin D and the atherogenic index of plasma (AIP) in a large general adult population (n = 9637) from the NHANES |
VD, vitamin D; VDR, vitamin D receptor; T2D, type 2 diabetes; BMI, body mass index; COPD, chronic obstructive pulmonary disease; KD, Kawasaki disease.