Table 3.

Coefficients of determination (R2) for each latent variable in our PLSs path model

Latent variable	R 2	CI95	Average variance extracted
Typically developing children and children with demyelinating disorders
Structural connectivity	0.47	0.23, 0.67	0.68
Pro-saccade functional connectivity	0.40	0.24, 0.68	0.62
Anti-saccade functional connectivity	0.50	0.24, 0.63	0.64
Pro-saccade reaction time	0.51	0.23, 0.80	-
Anti-saccade reaction time	0.56	0.43, 0.84	-
Pro-saccade direction errors	0.57	0.16, 0.93	-
Anti-saccade direction errors	0.44	0.18, 0.64	-
Children diagnosed with multiple sclerosis
Structural connectivity	0.26	0.14, 0.59	0.76
Pro-saccade functional connectivity	0.59	0.20, 0.79	0.72
Anti-saccade functional connectivity	0.54	0.13, 0.77	0.71
Pro-saccade reaction time	0.40	0.15, 0.78	-
Anti-saccade reaction time	0.45	0.17, 0.72	-
Pro-saccade direction errors	0.57	0.23, 0.72	-
Anti-saccade direction errors	0.43	0.14, 0.68	-
Children diagnosed with myelin oligodendrocyte glycoprotein-associated disorders
Structural connectivity	0.46	0.24, 0.92	0.74
Pro-saccade functional connectivity	0.57	0.37, 0.95	0.69
Anti-saccade functional connectivity	0.54	0.46, 0.94	0.70
Pro-saccade reaction time	0.43	0.29, 0.82	-
Anti-saccade reaction time	0.35	0.31, 0.89	-
Pro-saccade direction errors	0.49	0.22, 0.69	-
Anti-saccade direction errors	0.53	0.27, 0.82	-