TABLE 1.
Patient characteristics according to the occurrence of vasospasm requiring treatment with nimodipine.
| Characteristic | Vasospasm treated with nimodipine | ASD, % | |
|---|---|---|---|
| No (n = 13,244) | Yes (n = 434) | ||
| Age, years, mean (SD) a | 70.5 ± 14.9 | 62.3 ± 15.4 | 54.0 |
| Men, n (%) | 6843 (51.7) | 224 (51.6) | 0.2 |
| Mothership admission a | 5258 (39.7) | 175 (40.3) | 6.2 |
| Unknown time of onset a | 4394 (33.2) | 166 (38.2) | 10.5 |
| History of hypertension a | 8012 (60.5) | 220 (50.8) | 19.6 |
| History of hypercholesterolemia | 4145 (31.3) | 101 (23.2) | 18.3 |
| History of diabetes mellitus | 2413 (18.2) | 51 (11.7) | 18.3 |
| Current smoker | 2515 (19.0) | 132 (30.4) | 26.7 |
| Pre‐stroke antithrombotic treatment a | 5690 (43.0) | 144 (33.3) | 20.1 |
| Admission systolic blood pressure, mean (SD) | 148.7 ± 48.9 | 144.2 ± 27.5 | 13.6 |
| Admission diastolic blood pressure, mean (SD) | 82.9 ± 31.9 | 82.3 ± 17.4 | 2.4 |
| Admission NIHSS score, median (IQR) a | 16 (10 to 20) | 15 (9 to 20) | 6.1 |
| Baseline ASPECTS, median (IQR) | 8 (6 to 9) | 8 (6 to 9) | 7.9 |
| Pre‐stroke mRS score >1 a | 1631 (12.3) | 35 (8.0) | 14.3 |
| Site of intracranial occlusion a | |||
| Intracranial ICA | 1608 (12.1) | 70 (16.2) | 20.6 |
| M1 | 6558 (49.5) | 196 (45.2) | |
| M2 | 1863 (14.1) | 66 (15.3) | |
| Tandem | 1455 (11.0) | 57 (13.2) | |
| Vertebro baslilar | 1015 (7.7) | 18 (4.1) | |
| Isolated extracranial ICA | 308 (2.3) | 12 (2.8) | |
| Others/multiple | 438 (3.3) | 14 (3.3) | |
| Intravenous thrombolysis a | 6711 (50.7) | 175 (40.3) | 20.9 |
| General anesthesia | 3120 (23.6) | 162 (37.4) | 30.5 |
| Stroke etiology | |||
| Dissection | 520 (3.9) | 36 (8.4) | 20.9 |
| Cardioembolic | 6038 (45.6) | 164 (37.8) | |
| Large artery atherosclerosis | 2040 (15.4) | 81 (18.8) | |
| Carotid web | 77 (0.6) | 5 (1.2) | |
| Others/multiple/undetermined | 4569 (34.5) | 147 (33.9) | |
| Onset to imaging, min, median (IQR) | 126 (91 to 180) | 137 (100 to 191) | 15.7 |
| Onset to arterial puncture, median (IQR) | 265 (197 to 348) | 274 (210 to 362) | 11.1 |
Note: Values are expressed as number (%) unless otherwise indicated. Values were calculated after handing missing data using multiple imputation procedure.
Abbreviations: ASD, absolute standardized difference; ASPECTS, Alberta Stroke Program Early CT Score; EVT, endovascular therapy; ICA, internal carotid artery; IQR, interquartile range; IVT, intravenous thrombolysis; NIHSS, National Institutes of Health Stroke Scale; SD, standard deviation.
a
Included in propensity score.