Table 9.

Biomarkers corresponding to all the virtual CRT configurations varying Ventriculo-Ventricular Delay (VVD) with the left electrode positioned at LEAS. Positive values of VVD mean that the right stimulation occurs before the left one. For CRT scenarios we indicate the percentage of variation of ${dP/dt|}_{\text{max}}$, SV and SW with respect to the pre-operative case, whereas for EF we indicate the absolute changes. P2, P3, P4: non-fibrotic cases; P6, P8, P11: fibrotic cases

Patient	Delay	${dP/dt|}_{\mathit{max}}$	$\mathit{SV}$	$\mathit{EF}$	$\mathit{SW}$
	[ms]	$[{\text{mmHg}}^{-1}]$	$[\mathit{ml}]$	$[\%]$	$[\text{mmHg}ml]$
P2	Pre-operative	2252	76	15.1	6300
	$-30$	$+4.3\%$	$+7.9\%$	$+1.4$	$+13.0\%$
	$-15$	$+5.2\%$	$+10.5\%$	$+1.6$	$+17.0\%$
	0	$+7.4\%$	$+11.8\%$	$+1.8$	$+19.0\%$
	15	$+9.3\%$	$+11.8\%$	$+1.8$	$+20.0\%$
	30	$+11.3\%$	$+10.5\%$	$+1.7$	$+18.0\%$
P3	Pre-operative	3119	112	31.9	11, 600
	$-30$	$+2.9\%$	$+5.4\%$	$+1.7$	$+9.0\%$
	$-15$	$+7.0\%$	$+7.1\%$	$+2.3$	$+12.2\%$
	0	$+13.0\%$	$+8.0\%$	$+2.6$	$+14.8\%$
	15	$+17.7\%$	$+8.9\%$	$+2.9$	$+16.2\%$
	30	$+24.9\%$	$+8.9\%$	$+2.8$	$+16.6\%$
P4	Pre-operative	2278	73	24.5	6800
	$-30$	$-0.1\%$	$+5.3\%$	$+1.3$	$+8.0\%$
	$-15$	$+1.2\%$	$+6.2\%$	$+1.5$	$+9.8\%$
	0	$+6.5\%$	$+7.3\%$	$+1.8$	$+10.8\%$
	15	$+9.8\%$	$+7.6\%$	$+1.8$	$+10.9\%$
	30	$+9.1\%$	$+6.9\%$	$+1.7$	$+9.8\%$
P6	Pre-operative	2186	82	25.9	7000
	$-30$	$+1.6\%$	$+10.9\%$	$+2.8$	$+15.2$
	$-15$	$+2.4\%$	$+11.5\%$	$+3.0$	$+16.6\%$
	0	$+3.7\%$	$+11.8\%$	$+3.0$	$+16.9\%$
	15	$+5.1\%$	$+10.6\%$	$+2.7$	$+15.4\%$
	30	$+6.7\%$	$+9.7\%$	$+2.5$	$+13.4\%$
P8	Pre-operative	2731	70	32.9	6700
	$-30$	$-3.1\%$	$+1.4\%$	$+0.6$	$+1.3\%$
	$-15$	$-0.9\%$	$+2.8\%$	$+1.1$	$+6.9\%$
	0	$+2.0\%$	$4.2\%$	$+1.4$	$+6.6\%$
	15	$+3.0\%$	$+4.2\%$	$+1.5$	$+6.9\%$
	30	$+3.2\%$	$+2.8\%$	$+1.1$	$+5.4\%$
P11	Pre-operative	2460	58	25.0	4900
	$-30$	$-0.1\%$	$+5.2\%$	$+1.5$	$+8.6\%$
	$-15$	$+0.5\%$	$+6.9\%$	$+2.1$	$+12.4\%$
	0	$+0.7\%$	$+10.3\%$	$+2.6$	$+15.6\%$
	15	$-0.9\%$	$+8.6\%$	$+2.2$	$+13.2\%$
	30	$-1.7\%$	$+6.9\%$	$+1.7$	$+9.0\%$