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. 2024 Nov 3;41(11):907–913. doi: 10.1007/s40266-024-01153-6

Table 2.

Proportions of different drug classes/drugs among individuals with major NCD and reference individuals

Major NCD Reference group p-Valuea
Number of individuals 10,540 12,287 NA
RAS inhibitors 5941 (56.4) 8532 (69.4) <0.001
BBs 6842 (64.9) 8879 (72.3) <0.001
MRAs 1852 (17.6) 3014 (24.5) <0.001
Loop diuretics 5927 (56.2) 6657 (54.2) 0.002
Digitalis glycosides 1043 (9.9) 1215 (9.9) 0.986
SGLT2 inhibitors 120 (1.1) 195 (1.6) 0.004

Data are expressed as n (%)

BBs β-blockers, MRAs mineralocorticoid receptor antagonists, NCD neurocognitive disorder, RAS renin-angiotensin system, SGLT2 sodium-glucose linked transporter-2, NA not available

aChi-square tests