Table 2.
Cell type | Phenotype | Age category | Mean | SD | p value | |
---|---|---|---|---|---|---|
Immune cells | CD45+ | cell/ml | Young | 63 550 | 23 890 | 0,262 |
Old | 47 120 | 23 939 | ||||
% (of all cells) | Young | 58,1% | 14% | 0,648 | ||
Old | 54,5% | 13% | ||||
Resident & M2 macrophages | CD45 + CD163+ | cell/ml | Young | 11 725 | 6 502 | 0,677 |
Old | 10 099 | 6 614 | ||||
% (of CD45+) | Young | 19,8% | 10% | 0,643 | ||
Old | 22,2% | 8% | ||||
Other immune cells | CD45 + CD163- | cell/ml | Young | 50 790 | 21 744 | 0,235 |
Old | 35 922 | 18 950 | ||||
% (of CD45+) | Young | 78,4% | 10% | 0,613 | ||
Old | 75,6% | 8% | ||||
Non-immune cells | CD45- | cell/ml | Young | 43 165 | 16 393 | 0,714 |
Old | 38 827 | 22 869 | ||||
% (of CD45-) | Young | 41,5% | 14% | 0,704 | ||
Old | 44,5% | 13% | ||||
ASC |
CD45- CD31- CD34+ |
cell/ml | Young | 22 815 | 10 455 | 0,818 |
Old | 30 001 | 18 495 | ||||
% (of CD45-) | Young | 52,5% | 18% | 0,009* | ||
Old | 77,5% | 13% | ||||
Endothelial cells |
CD45- CD31 + CD34+ |
cell/ml | Young | 8 847 | 4 375 | 0,014* |
Old | 2 782 | 2 374 | ||||
% (of CD45-) | Young | 23,5% | 16% | 0,054 | ||
Old | 7,2% | 5% | ||||
Pericytes |
CD45- CD31- CD34- CD146+ |
cell/ml | Young | 4 439 | 2 242 | 0,240 |
Old | 2 763 | 3 481 | ||||
% (of CD45-) | Young | 9,9% | 4% | 0,132 | ||
Old | 7,6% | 13% |