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. 2024 Nov 11;14:27589. doi: 10.1038/s41598-024-73875-x

Table 2.

Quantification of cell populations in the SVF and their repartition among CD45- and CD45 + populations. n = 6 donors were used in each age category. * p value < 0,05 indicated in bold. Unpaired Wilcoxon test was used to test the significance of ASC and pericytes populations. Unpaired student t-test was used to test the significance of other cell populations.

Cell type Phenotype Age category Mean SD p value
Immune cells CD45+ cell/ml Young 63 550 23 890 0,262
Old 47 120 23 939
% (of all cells) Young 58,1% 14% 0,648
Old 54,5% 13%
Resident & M2 macrophages CD45 + CD163+ cell/ml Young 11 725 6 502 0,677
Old 10 099 6 614
% (of CD45+) Young 19,8% 10% 0,643
Old 22,2% 8%
Other immune cells CD45 + CD163- cell/ml Young 50 790 21 744 0,235
Old 35 922 18 950
% (of CD45+) Young 78,4% 10% 0,613
Old 75,6% 8%
Non-immune cells CD45- cell/ml Young 43 165 16 393 0,714
Old 38 827 22 869
% (of CD45-) Young 41,5% 14% 0,704
Old 44,5% 13%
ASC

CD45-

CD31-

CD34+

cell/ml Young 22 815 10 455 0,818
Old 30 001 18 495
% (of CD45-) Young 52,5% 18% 0,009*
Old 77,5% 13%
Endothelial cells

CD45-

CD31 + 

CD34+

cell/ml Young 8 847 4 375 0,014*
Old 2 782 2 374
% (of CD45-) Young 23,5% 16% 0,054
Old 7,2% 5%
Pericytes

CD45-

CD31-

CD34-

CD146+

cell/ml Young 4 439 2 242 0,240
Old 2 763 3 481
% (of CD45-) Young 9,9% 4% 0,132
Old 7,6% 13%