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. 2024 Nov 11;14:27577. doi: 10.1038/s41598-024-79207-3

Table 3.

The cross-sectional association of UNa-K ratio and phenotypes of elevated BP.

HTN phenotypes UNa-K ratio
Q2-Q4
1.23–3.14
Q5
≥ 3.14
Per 1 SD
ISH
 Crude 2.27 (0.79–6.56) 3.04 (0.96–9.58) 1.23 (0.78–1.95)
 Model 1 2.37 (0.81–6.95) 3.08 (0.96–9.93) 1.24 (0.78–1.97)
 Model 2 2.33 (0.79–6.86) 3.00 (0.93–9.69) 1.21 (0.76–1.93)
IDH
 Crude 0.85 (0.65–1.10) 0.82 (0.58–1.14) 0.86 (0.71–1.04)
 Model 1 0.83 (0.64–1.09) 0.82 (0.58–1.14) 0.87 (0.72–1.05)
 Model 2 0.83 (0.63–1.07) 0.81 (0.58–1.14) 0.86 (0.71–1.05)
SDH
 Crude 1.19 (0.73–1.96) 1.79 (1.03–3.13) 1.32 (1.01–1.71)
 Model 1 1.24 (0.75–2.07) 1.86 (1.05–3.31) 1.33 (1.01–1.74)
 Model 2 1.21 (0.73–2.03) 1.79 (1.09–3.19) 1.29 (1.00-1.70)

Data are RRRs (95% CI); Model 1 was adjusted for age, sex, BMI, eGFR, and urinary creatinine; Model 2 was additionally adjusted for physical activity level and smoking. Multinomial logistic regression models were used (Q1 was considered as reference category).

HTN phenotypes were defined as: ISH (SBP ≥ 130 and DBP < 80 mmHg), IDH (SBP < 130 and DBP ≥ 80 mmHg), and SDH (SBP ≥ 130 and DBP ≥ 80 mmHg).

UNa-K ratio: Q1 < 1.23, 1.23 ≤ Q2–Q4 < 3.14, Q5 ≥ 3.14.

Median of UNa-K ratio was 0.91, 2.01, and 4.05 in Q1, Q2–Q4, and Q5, respectively.

HTN hypertension, ISH isolated systolic hypertension, IDH isolated diastolic hypertension, SDH combined systolic and diastolic hypertension.