Table 2. Frequency of Device Complications in Patients Receiving Outpatient Parenteral Antimicrobial Therapy by Device Type.
| Outcome | No. (%) | P value | ||
|---|---|---|---|---|
| Total (N = 2824) | Midline catheter (n = 1999) | PICC (n = 825) | ||
| Any major complication | 44 (1.6) | 16 (0.8) | 28 (3.4) | <.001 |
| Catheter-related BSI | 20 (0.7) | 5 (0.23) | 15 (1.8) | <.001 |
| Catheter-related VTE | 26 (0.9) | 11 (0.6) | 15 (1.8) | .001 |
| Upper-extremity DVT | 22 (0.8) | 11 (0.6) | 11 (1.3) | .03 |
| Pulmonary embolism | 4 (0.1) | 0 | 4 (0.5) | .002 |
| Any minor complication | 320 (11.3) | 206 (10.3) | 114 (13.8) | .007 |
| Catheter dislodgement | 120 (4.2) | 75 (3.8) | 45 (5.5) | .04 |
| Catheter occlusion | 82 (2.9) | 45 (2.3) | 37 (4.5) | .001 |
| Catheter tip migration | 58 (2.1) | 22 (1.1) | 36 (4.4) | <.001 |
| Infiltration | 9 (0.3) | 9 (0.5) | 0 | NA |
| Superficial thrombosis | 18 (0.6) | 16 (0.8) | 2 (0.2) | .09 |
| Exit site concerns | 81 (2.9) | 72 (3.6) | 9 (1.1) | <.001 |
| Any major or minor complication | 352 (12.5) | 215 (10.8) | 137 (16.6) | <.001 |
| Device failure | 291 (10.3) | 191 (9.6) | 100 (12.1) | .04 |
Abbreviations: BSI, bloodstream infection; DVT, deep vein thrombosis; NA, not applicable; PICC, peripherally inserted central catheter; VTE, venous thromboembolism.