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Low-grade somatic instability of HTT repeats in three patients with reduced penetrance or intermediate alleles. RP-PCR was performed to assess CAG-repeat numbers in HTT. (A-C) Repeat numbers in nucleus caudatus of autopsy samples from three individuals. Y-axis indicate signal strength of the analyzed sample. The high and narrow peaks in the enlarged section (to the right in the picture) are size standard peaks used for size assessment.
