Table 4.
Ciprofol | Propofol | |
---|---|---|
Chemical Formula |
C14H20O (R)-2-(1-cyclopropylethyl)-6-isopropylphenol |
C12H18O 2,6-diisopropylphenol |
pKa Value | 11.8 | 11.1 |
Potency Difference | 5 more potent than propofol | - |
Solution Type | Lipid-in-water solution | Lipid-based solution |
Complications | Hypotension, bradycardia, apnea, respiratory depression, hypoxia | Propofol infusion syndrome |
Dosage (Adults) | 0.4 mg/kg | Typically 1.5–2.5 mg/kg for induction, followed by maintenance infusion rates |
Dosage (Children) | - | Typically 1–3 mg/kg for induction, followed by maintenance infusion rates |
Cost Difference | 1–2 times higher than propofol | Varies depending on the region and brand |