Table 5.
Univariable and Multivariable Logistic Regression Analysis of Postoperative complications
| Variable | Univariable Logistic Analysis | Multivariable Logistic Analysis | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Age, y | ||||||
| < 75 | 1 | Reference | - | - | - | - |
| ≥ 75 | 1.652 | 0.604–4.562 | 0.329 | - | - | - |
| Sex | ||||||
| Male | 1 | Reference | - | - | - | - |
| Female | 0.723 | 0.216–2.117 | 0.598 | - | - | - |
| Preoperative BMI | 0.806 | 0.547–1.311 | 0.369 | - | - | - |
| ASA physical status classification | ||||||
| II | 1 | Reference | - | - | - | - |
| III | 0.875 | 0.407–2.083 | 0.766 | - | - | - |
| IV | 1.072 | 0.374–3.158 | 0.910 | - | - | - |
| Fried Frailty Index | ||||||
| 2 | 1 | Reference | - | - | - | - |
| 3 | 1.465 | 0.545–3.831 | 0.446 | - | - | - |
| 4 | 1.725 | 0.722–4.156 | 0.219 | - | - | - |
| 5 | 1.594 | 0.333–2.942 | 0.611 | - | - | - |
| Charlson comorbidity index | ||||||
| < 3 | 1 | Reference | - | - | - | - |
| ≥ 3 | 2.351 | 1.380–4.022 | 0.002 | 2.017 | 1.241–3.816 | 0.027 |
| Smoking status | ||||||
| None | 1 | Reference | - | - | - | - |
| Current | 1.079 | 0.371–2.425 | 0.872 | - | - | - |
| Alcohol use | ||||||
| None | 1 | Reference | - | - | - | - |
| Current | 1.158 | 0.564–2.397 | 0.708 | - | - | - |
| Metabolic status | ||||||
| Preoperative C-reactive protein level | 0.939 | 0.804–1.131 | 0.476 | - | - | - |
| Preoperative albumin level | 0.815 | 0.573–1.169 | 0.244 | - | - | - |
| Preoperative hemoglobin level | 0.901 | 0.636–1.318 | 0.281 | - | - | - |
| Pathological TNM stage a | ||||||
| I | 1 | Reference | - | - | - | - |
| II | 1.532 | 0.862–2.747 | 0.155 | - | - | - |
| III | 1.056 | 0.531–2.104 | 0.921 | - | - | - |
| Aerobic capacity | ||||||
| Baseline 6MWD ≥ 400 m | 1 | Reference | - | - | - | - |
| Baseline 6MWD < 400 m | 1.498 | 0.526–2.208 | 0.262 | - | - | - |
| Multimodal prehabilitation | ||||||
| Yes | 1 | Reference | - | - | - | - |
| No | 2.009 | 1.061–3.512 | 0.008 | 1.971 | 1.232–3.195 | 0.039 |
| Estimated blood loss | 0.425 | 0.151–1.239 | 0.121 | - | - | - |
| Duration of surgery | 0.820 | 0.459–1.261 | 0.593 | - | - | - |
| Intraoperative transfusion | 1.026 | 0.702–1.479 | 0.918 | |||
| Surgical approach | ||||||
| Minimally invasive | 1 | Reference | - | |||
| Open | 0.815 | 0.483–1.625 | 0.581 | - | ||
| Intraoperative transfusion | 1.018 | 0.714–1.463 | 0.922 | |||
Abbreviations: 6-MWD 6-minute walking distance, ASA American Society of Anesthesiologists, BMI body mass index, CI confidence interval, OR odds ratio, TNM tumor, node, metastasis