Table 4. Magnetic Resonance Imaging classification of amyloid-related imaging abnormalities 34 .
ARIA type | Radiographic severity | ||
---|---|---|---|
Mild | Moderate | Severe | |
ARIA-E | FLAIR hyperintensity confined to sulcus and/or cortex/subcortex white matter in one location <5 cm | FLAIR hyperintensity 5–10 cm in single greatest dimension, or more than one site of involvement each measuring <10 cm | FLAIR hyperintensity >10 cm with gyral swelling and sulcal effacement. One or more sites may be noted. |
ARIA-H microhemorrhages | <4 new incident microhemorrhages | 5–9 new incident microhemorrhages | ≥10 new incident microhemorrhages |
ARIA-H superficial siderosis | One focal area of superficial siderosis | Two focal areas of superficial siderosis | More than two focal areas of superficial siderosis |
Abbreviations: FLAIR, fluid-attenuated inversion recovery; ARIA-E, amyloid-related imaging abnormality with edema and effusion; ARIA-H, amyloid-related imaging abnormality with hemosiderin deposits.