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. Author manuscript; available in PMC: 2024 Nov 12.
Published in final edited form as: J Med Chem. 2023 Aug 19;66(17):11701–11717. doi: 10.1021/acs.jmedchem.3c00750

Figure 3.

Figure 3.

Antiviral effect of oral 3 on respiratory tract lavage, swab, and tissue samples in the African green monkey SARS-CoV-2 infection model. (A) Infectious virus in bronchoalveolar lavage fluid (BALF). (B) Genomic RNA in BALF. (C) Infectious viral titer in throat swab. (D) Genomic RNA in throat swab. (E) Genomic RNA in respiratory tissue samples harvested day 6 across the respiratory tract. LLOQ, lower limit of quantification. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.