Table 2.
Characteristics and baseline Eye ACT study visit data from the eye with worse visual acuity in the first 300 prospective Eye ACT study clinic visit participants and 30 home visit participants.
| Clinic visit (N=300) | Home visit (N=30) | p-valueb | |||
|---|---|---|---|---|---|
|
| |||||
| Na | Mean (SD) or % | N1 | Mean (SD) or % | ||
|
| |||||
| Number of ACT visits as of 03/2023 | 300 | 3.3 (2.1) | 30 | 4.5 (2.2) | 0.003 |
|
| |||||
| Age at Eye ACT baseline | 300 | 74.9 (4.9) | 30 | 77.2 (5.7) | 0.015 |
|
| |||||
| Female sex | 300 | 49% | 30 | 60% | 0.026 |
|
| |||||
| Race c | 300 | 30 | 0.73 | ||
| White | 92.30% | 93.30% | |||
| Black | 0.30% | 0% | |||
| Asian | 2.70% | 0% | |||
| Mixed race or Other | 4.70% | 6.70% | |||
|
| |||||
| Education at ACT baseline (years) | 300 | 17.8 (2.4) | 30 | 17.0 (2.6) | 0.15 |
|
| |||||
| CASI-IRT scored | 297 | 0.00 (1.0) | 30 | 0.03 (1.1) | 0.97 |
|
| |||||
| Visual Acuity (ETDRS)e,f | 298 | 78.9 (8.9) | 29 | 71.1(15.6) | < 0.001 |
|
| |||||
| Contrast Sensitivity, 6CPD logf,g | 297 | -1.73 (0.40) | 29 | -1.46 (0.61) | 0.003 |
|
| |||||
| Contrast Sensitivity, 3CPD logf,g | 297 | -2.06 (0.37) | 29 | -1.85 (0.61) | 0.002 |
|
| |||||
| Intraocular pressure, mmHgf | 264 | 14.2 (4.0) | 29 | 13.6 (3.5) | 0.46 |
|
| |||||
| Total macular thickness, mmf | 247 | 266.8 (17.1) | 29 | 266.4 (26.5) | 0.37 |
|
| |||||
| Total foveal thickness, mmf | 247 | 214.4 (41.1) | 29 | 227.6 (60.9) | 0.27 |
|
| |||||
| Macular RNFL thickness, mmf | 247 | 33.9 (6.8) | 29 | 31.5 (7.7) | 0.14 |
|
| |||||
| Macular GC-IPL thickness, μmf | 247 | 63.8 (7.2) | 29 | 64.8 (10.2) | 0.89 |
ACT, Adult Changes in Thought; CASI-IRT, Cognitive Abilities Screening Instrument-Item Response Theory; ETDRS, Early Treatment Diabetic Retinopathy Study; CPD, cycles per degree; GC-IPL, ganglion cell/inner plexiform layer; RNFL, retinal nerve fiber layer.
Reasons for missing data included incomplete data collection, patient related factors, or insufficient data quality for analysis.
Wilcoxon rank sum for continuous variables, Fisher’s exact for categorical.
ACT participants self-identified their race.
IRT-based CASI score, standardized to a mean of 0 (SD 1) in this Eye ACT sample at the nearest ACT biennial visit before the initial Eye ACT visit.
Early Treatment Diabetic Retinopathy Study visual acuity scores. Higher ETDRS values indicate better visual acuity.
Data from the worst visual acuity eye.
More negative log value indicates better contrast sensitivity.