Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Components of Hippo pathway in Drosophila and mammals.
| In Drosophila | Ortholog in mammals |
|---|---|
| Hippo (Hpo) | Mammalian sterile 20-like kinase1/2 (MST1/2) |
| Salvador (Sav) | Salvador homolog-1 (SAV1) |
| Warts (Wts) | Large tumor suppressor1/2 (LATS1/2) |
| Mob as tumor suppressor (Mats) | Mps One Binder kinase activator protein 1 (MOB1) |
| Yorkie (Yki) | Yes associated protein/transcriptional coactivator with PDZ-binding motif (YAP/TAZ) |
| Scalloped (Sd) | TEA domain family member (TEAD1/2/3/4) |
