Table 4.
Significant outcome predictors for MI, all-cause death, CV death, and repeated PCI procedures in Cox proportion hazard model.
Variables | MI | All-cause mortality | CV mortality | Repeated PCI | ||||
---|---|---|---|---|---|---|---|---|
Crude HR (95% CI) |
Adjusted HR (95% CI) |
Crude HR (95% CI) |
Adjusted HR (95% CI) |
Crude HR (95% CI) |
Adjusted HR (95% CI) |
Crude HR (95% CI) |
Adjusted HR (95% CI) |
|
Age | 0.99 (0.94–1.04) | 0.95 (0.89–1.01) | 1.05 (1.02–1.08)** | 1.05 (1.02–1.09)** | 1.03 (0.99–1.07) | 0.98 (0.93–1.03) | 1.00 (0.98–1.01) | 0.99 (0.98–1.01) |
DM | 1.09 (0.37–3.19) | 1.63 (0.54–4.94) | 1.25 (0.67–2.34) | 1.21 (0.61–2.40) | 1.34 (0.60–2.99) | 0.63 (0.24–1.71) | 1.26 (0.91–1.75) | 1.21 (0.87–1.67) |
ACS | 1.86 (0.68–5.09) | 1.06 (0.35–3.17) | 2.43 (1.29–4.57)** | 1.16 (0.59–2.28) | 3.52 (1.44–8.59)** | 1.91 (0.75–4.86) | 1.22 (0.89–1.67) | 1.26 (0.92–1.73) |
CKD | 1.54 (0.44–5.33) | 1.11 (0.23–5.34) | 1.00 (0.47–2.14) | 1.59 (0.70–3.60) | 0.80 (0.29–2.19) | 1.27 (0.39–4.18) | 1.19 (0.81–1.76) | 1.08 (0.73–1.60) |
Stroke | – | – | 1.15 (0.43–3.06) | 0.90 (0.30–2.64) | 1.78 (0.56–5.71) | 5.27 (1.25–22.14)* | 1.43 (0.68–3.04) | 1.64 (0.77–3.51) |
Syntax score | 1.07 (1.02–1.12)* | 1.11 (1.04–1.18)** | 1.04 (1.01–1.07)* | 1.04 (1.01–1.08)* | 1.06 (1.02–1.10)** | 1.03 (0.99–1.09) | 1.00 (0.98–1.02) | 1.00 (0.98–1.02) |
DES | 1.05 (0.36–3.08) | 1.08 (0.30–3.85) | 0.59 (0.30–1.16) | 0.63 (0.29–1.34) | 0.66 (0.29–1.52) | 0.97 (0.34–2.75) | 1.08 (0.78–1.49) | 1.09 (0.79–1.50) |
Aspirin | – | – | 2.06 (0.73–5.83) | 1.07 (0.36–3.22) | 4.47 (0.59–33.80) | 0.72 (0.07–6.98) | 1.82 (0.95–3.48) | 1.63 (0.85–3.13) |
P2Y12 inhibit | 1.86 (0.23–15.01) | 1.46 (0.16–13.43) | 1.75 (0.66–4.61) | 1.67 (0.56–4.98) | 2.61 (0.58–11.73) | 1.29 (0.19–8.69) | 1.86 (1.10–3.14)* | 1.86 (1.09–3.15)* |
BB | 1.75 (0.66–4.62) | 2.46 (0.76–7.76) | 0.43 (0.23–0.81)** | 0.49 (0.24–1.00) | 0.38 (0.17–0.86)* | 1.61 (0.45–5.75) | 1.13 (0.84–1.52) | 1.12 (0.83–1.50) |
CCB | 1.69 (0.55–5.15) | 0.90 (0.25–3.16) | 0.55 (0.25–1.22) | 0.55 (0.24–1.29) | 0.54 (0.18–1.63) | 0.30 (0.06–1.37) | 1.01 (0.71–1.43) | 0.98 (0.69–1.38) |
ACEI | 1.42 (0.50–4.01) | 1.05 (0.31–3.57) | 0.59 (0.29–1.22) | 0.66 (0.30–1.41) | 0.64 (0.26–1.58) | 0.88 (0.30–2.61) | 0.60 (0.42–0.85)** | 0.54 (0.37–0.77)** |
Statin | 0.54 (0.19–1.56) | 0.53 (0.16–1.70) | 0.22 (0.09–0.53)** | 0.27 (0.10–0.75)* | 0.20 (0.06–0.62)** | 0.32 (0.07–1.49) | 0.86 (0.63–1.17) | 0.84 (0.61–1.61) |
ACEI = angiotensin-converting enzyme inhibitor, ACS = previous acute coronary syndrome, BB = beta-blockers, CCB = calcium channel blocker, CKD = chronic kidney disease, CPP = central pulse pressure, CV mortality = cardiovascular mortality, DES = drug-eluting stent, DM = diabetes mellitus, MI = myocardial infarction, P2Y12 inhibitor = P2Y12 receptor inhibitor of platelet, SYNTAX score = Synergy Between PCI With Taxus and Cardiac Surgery score.
P < .05.
P < .01.