TABLE 7.

Result of the in vivo micronucleus test in mice with Organic Cordyceps M2-116-04 powder.

Treatment group	Dose	Number of PCE with micronuclei per 2000 PCE	PCE/NCE ratio
Vehicle control	10 mL/kg bw, 24 h	0.8 ± 0.6	0.65 ± 0.13
Positive control	50 mg/kg bw, 24 h	51.7 ± 18.0**	0.65 ± 0.13
Organic Cordyceps M2-116-04 powder	300 mg/kg bw, 24 h	0.8 ± 0.8	0.65 ± 0.13
	1000 mg/kg bw, 24 h	1.4 ± 0.9	0.49 ± 0.31
	2000 mg/kg bw, 24 h	1.5 ± 0.9	0.51 ± 0.14
Organic Cordyceps M2-116-04 powder satellite	2000 mg/kg bw, 48 h	1.9 ± 1.0	0.52 ± 0.14

Data shown as mean ± SD.

**Statistical significance compared to vehicle control, p < 0.01.

PCE: polychromatic erythrocytes; NCE: normochromatic erythrocytes.

Vehicle control–phosphate buffered saline; Positive Control–cyclophosphamide.