Table 3.
Univariate and Multivariate Risk analysis for PROM in pregnant women after cervical conization
| Index | Univariate | Multivariate | ||
|---|---|---|---|---|
|
|
|
|||
| OR [95% CI] | P value | OR [95% CI] | P value | |
| Age | ||||
| <35 years | Reference | Reference | ||
| ≥35 years | 1.68 [0.5989-0.973] | 0.006 | 2.754 [1.251-2.749] | 0.011 |
| BMI before pregnancy | ||||
| <24 | Reference | Reference | ||
| 24-28 | 1.82 [0.9206-1.982] | 0.047 | 1.24 [0.85-1.85] | 0.281 |
| ≥28 | 1.42 [0.9378-1.515] | 0.1297 | 2.97 [1.75-2.05] | 0.005 |
| Multipara | ||||
| Yes | Reference | |||
| No | 0.46 [0.133-1.636] | 0.234 | ||
| Assisted reproduction and pregnancy | ||||
| Yes | Reference | Reference | ||
| No | 0.43 [0.133-0.636] | 0.004 | 1.28 [0.77-1.38] | 0.261 |
| CL | ||||
| ≥25 | Reference | Reference | ||
| <25 | 1.25 [1.1615-1.189] | 0.028 | 1.754 [1.241-2.479] | 0.001 |
| Operation mode | ||||
| LEEP | Reference | |||
| CKC | 1.18 [1.09-2.23] | 0.294 | ||
| Cervical canceration | ||||
| CIN1 | Reference | Reference | ||
| CIN2 | 1.95 [0.6390-0.6522] | 0.022 | 1.58 [0.77-0.38] | 0.056 |
| CIN3 | 2.52 [0.9206-0.982] | 0.051 | 2.42 [0.85-0.95] | 0.058 |
| Time after conization | ||||
| 6-12 months | Reference | Reference | ||
| 12-24 months | 1.62 [0.639-0.928] | 0.014 | 1.55 [1.014-1.09] | 0.032 |
| >24 months | 5.95 [0.639-0.652] | 0.012 | 2.58 [0.57-0.88] | 0.006 |
Note: CL: cervical length; LEEP: Loop Electrosurgical Excision Procedure; CKC: Cold Knife Conization; CIN: Cervical Intraepithelial Neoplasia; PROM: premature rupture of membrane.