Table 3.
Comparison of serum levels of IL-10 and GFAP among glioma patients with different clinicopathological features
Parameters | Cases | IL-10 (ng/L) | t/χ2 value | P value | GFAP (ng/L) | t/χ2 value | P value | |
---|---|---|---|---|---|---|---|---|
Gender | Male | 39 | 171.45±36.28 | 1.417 | 0.159 | 59.14±12.05 | 1.133 | 0.260 |
Female | 36 | 181.41±38.71 | 67.72±14.64 | |||||
Age | ≤60 years old | 41 | 172.63±27.28 | 0.850 | 0.397 | 57.28±10.92 | 0.827 | 0.410 |
>60 years old | 34 | 180.57±30.15 | 70.47±11.83 | |||||
Location | Loubus fromatis | 41 | 170.73±39.06 | 0.551 | 0.583 | 59.06±11.04 | 1.102 | 0.273 |
Temporal lobe | 21 | 171.93±28.07 | 57.14±10.85 | |||||
Parietal lobe | 7 | 171.71±27.94 | 58.29±11.73 | |||||
Others | 6 | 183.26±34.21 | 66.37±13.29 | |||||
Tumor diameter | ≤3 cm | 11 | 170.38±21.74 | 1.378 | 0.171 | 57.87±9.87 | 1.111 | 0.269 |
3-5 cm | 35 | 175.22±23.58 | 59.23±11.26 | |||||
>5 cm | 29 | 181.47±26.39 | 65.31±13.85 | |||||
KPS scores | <70 points | 38 | 175.57±24.67 | 0.837 | 0.405 | 61.26±12.24 | 0.845 | 0.399 |
≥70 points | 37 | 177.21±26.35 | 65.38±13.73 | |||||
WHO Class | I and II grading | 37 | 163.86±19.27 | 3.550 | <0.001 | 71.69±13.95 | 6.064 | <0.001 |
III and IV grading | 38 | 188.63±37.94 | 54.83±9.69 | |||||
Genotype of P53 | wild type | 44 | 157.19±26.38 | 6.034 | <0.001 | 73.95±16.17 | 6.050 | <0.001 |
Mutant type | 31 | 203.25±39.76 | 55.73±9.88 | |||||
Ki-67 expression | Low | 42 | 165.17±20.94 | 3.491 | <0.001 | 69.65±12.18 | 4.126 | <0.001 |
High | 33 | 190.25±40.17 | 58.19±11.75 |
Note: IL-10: Interleukin-10; GFPA: Glial fibrillary acidic protein; KPS: Karnofsky Performance Scale; WHO: World Health Organization; P53: Protein 53.