Figure 4.

The effects of PM on Nrf2 and NF-κB pathways in LPS-induced ALI mice. A. PM inhibited the activation of NF-κB. B. The inhibitory effect of PM on NF-κB nuclear translocation induced by LPS. C. Effects of PM treatment on the expression of Nrf2 and HO-1. D. Effects of PM treatment on the mRNA expression of Nrf2, NQO1, and HO-1. The statistical results are presented as mean ± standard deviation (x±s, n=10 in each group). Compared with control group, ***P < 0.001; compared with LPS group, #P < 0.05, ##P < 0.01, ###P < 0.001.