Table 1.

Manifestations of organ damage from cosmetic-related mercury poisoning

Tissue and organ	Clinical presentation
Oral cavity	Oral mucosal inflammation, excessive salivation, dysphagia, gum pain, and ulcers of the lips and tongue.
Digestive system	Hepatocyte necrosis, cholestatic liver disease, organic or functional gastrointestinal diseases.
Nervous system	Tremors, emotional instability, insomnia, memory loss, muscle twitching, headaches and abnormal sensory perceptions. Long-term mercury exposure may lead to gait instability, tremulous speech, blurred vision, and hearing loss.
Kidney	Membranous kidney disease, with mercury forming metallothionein complexes that damage renal tubules.
Others	Abnormal thyroid function, hypercoagulability, aplastic anemia, accelerated aging, and infertility.