Table 5.
Major factors that may affect overall mortality in sepsis and septic shock.
| CITRIS-ALI 2019 (35) | VITAMINS 2020 (32) | HYVCTTSSS 2020 (24) | ORANGES 2020 (27) | ACTS 2020 (29) | Wani 2020 (30) | ATESS 2020 (26) | VICTAS 2021 (25) | LOVIT 2022 (28) | |
|---|---|---|---|---|---|---|---|---|---|
| APACHE II or III Scores | NA | Vitamin C: 77.4 (29.7)* Control: 83.3(28.8) |
Vitamin C: 22.1 (8.4) Control: 23.8 (7.6) |
Vitamin C: 24 (7.6) Control: 24.9 (8.7) |
NA | Vitamin C: 18.5 [15–24.75] Control: 20 [14–24] |
Vitamin C:22 [14–32] Control: 22 [17–32] |
Vitamin C: 27 [22–33] Control: 27 [19–33] |
Vitamin C: 24.2 (7.4) Control:24.1 (7.9) |
| Vasopressor use | Vitamin C 64.3% Control: 71.1% |
Vitamin C: 100% Control: 100% |
Vitamin C: 55% Control: 60% |
Vitamin C: 82% Control: 68% |
Vitamin C: 100% Control: 100% |
Vitamin C: 92% Control: 76% |
Vitamin C: 100% Control: 100% |
Vitamin C: 36.9% Control: 39.1% |
Vitamin C: 99.8% Control: 100% |
| Steroids administration | Vitamin C: 67% Control: 65% |
Vitamin C: 42.1% Control: 37.5% |
N/A | Steroid was part of intervention group who received vitamin C Control: 41% |
Steroid was part of intervention group who received vitamin C Control: 14.1% |
N/A | Vitamin C: 58.5% Control: 50% |
Vitamin C:33% Control: 32% |
Vitamin C: 46.4% Control:45.4% |
Data reported as mean (SD) or median [IQR].