TABLE 1.

Descriptive statistics for the study cohorts.

	Multiple sclerosis (n = 41)	Healthy participants (n = 41)
Age (years, median [IQR])	39 [34.0–43.0]	37 [30.4–43.8]
Diagnosis (CIS:RRMS)	8:33	N/A
Disease duration (months, median [IQR])	59 [59–64]	N/A
EDSS (median [IQR])	1.5 [1–2.5]	N/A
SDMT (median [IQR])	63.5 [53–73.5]	63 [56–67]
Periventricular lesion volumes (mL, median [IQR])	0.61 [0.16–1.61]	0 [0–0.03]
Periventricular lesion count (median [IQR])	12 [5–27]	0 [0–2]
Deep lesion volumes (mL, median [IQR])	0.62 [0.21–2.23]	0.02 [0–0.06]
Deep lesion count (median [IQR])	21 [7–63]	1 [0–4]
Head motion during rs‐fMRI (mm, median [IQR])	0.18 [0.15–0.21]	0.16 [0.13–0.21]

Abbreviations: CIS = clinically isolated syndrome; EDSS = Expanded Disability Status Scale; IQR = interquartile range; RRMS = relapsing–remitting multiple sclerosis; rs‐fMRI = resting‐state functional magnetic resonance imaging; SDMT = Symbol Digit Modalities Test.