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. 2024 Nov 13;24:636. doi: 10.1186/s12872-024-04313-z

Table 1.

Comparison of participants by status of antihypertensive medication use; no antihypertension medications, only first-line medications, and only non-first-line medications, or combination of first-line and non-first-line medications

Antihypertensive medication status
No meds Only first-line meds Only non-first-line meds Combination meds p-value
Variable N = 157 N = 111 N = 21 N = 22
Age (mean (SD)) 33.04 (4.97) 34.90 (3.91) 32.19 (5.10) 35.09 (4.70) 0.001
Sex 0.008
 Male (%) 92 (58.6) 61 (55.0) 5 (23.8) 8 (36.4)
 Female (%) 65 (41.4) 50 (45.0) 16 (76.2) 14 (63.6)
Race (%) 0.001
 Black 22 (14.0) 36 (32.4) 4 (19.0) 10 (45.5)
 Other 12 (7.6) 9 (8.1) 4 (19.0) 2 (9.1)
 White non-Hispanic 123 (78.3) 66 (59.5) 13 (61.9) 10 (45.5)
Marital status (%) 0.144
 Single 42 (26.8) 42 (37.8) 8 (38.1) 12 (54.5)
 Married/partnered 111 (70.7) 66 (59.5) 13 (61.9) 10 (45.5)
 Divorced/widower 4 (2.5) 3 (2.7) 0 (0.0) 0 (0.0)
Highest level of education (%) 0.940
 I have not finished high school 6 (3.8) 6 (5.4) 0 (0.0) 3 (13.6)
 I have completed high school 22 (14.0) 15 (13.5) 3 (14.3) 2 (9.1)
 I have not finished college or vocation school 24 (15.3) 16 (14.4) 7 (33.3) 5 (22.7)
 I finished college or vocational school 73 (46.5) 53 (47.7) 7 (33.3) 4 (18.2)
 Some/completed Graduate or Professional School 32 (20.4) 21 (18.9) 4 (19.0) 8 (36.4)
Number of children at home (mean (SD)) 0.95 (1.38) 1.08 (1.43) 1.24 (1.41) 0.95 (1.12) 0.674
Ever been on Medicaid (%) 30 (19.1) 27 (24.3) 5 (23.8) 5 (22.7) 0.767
Weight (kg) (mean (SD)) 101.87 (30.75) 104.39 (25.08) 96.52 (26.37) 110.41 (26.12) 0.149
Waist circumference (cm) (mean (SD)) 107.42 (20.65) 111.21 (18.45) 107.67 (20.86) 116.45 (17.93) 0.091
Body mass index (kg/m2) (mean (SD)) 33.61 (9.37) 35.15 (8.41) 34.32 (8.16) 37.42 (6.81) 0.016
Office systolic BP (mmHg) (mean (SD)) 139.15 (13.99) 137.41 (13.98) 136.16 (16.20) 138.76 (16.86) 0.579
Office diastolic BP (mmHg) (mean (SD)) 91.42 (11.35) 90.57 (11.49) 93.16 (12.43) 94.14 (9.79) 0.230
Ambulatory systolic BP (mmHg) (mean (SD)) 133.10 (12.44) 132.79 (12.42) 129.86 (10.13) 134.86 (9.37) 0.368
Ambulatory diastolic BP (mmHg) (mean (SD)) 87.08 (8.45) 86.28 (7.89) 87.86 (6.46) 87.05 (6.26) 0.554
e-cigarette/vaping use in past 6 months (%) 15 (9.6) 9 (8.1) 2 (9.5) 0 (0.0) 0.504
Cigarette tobacco status (%) 0.929
 I currently smoke cigarettes 19 (12.1) 15 (13.5) 2 (9.5) 4 (18.2)
 I have never smoked cigarettes 105 (66.9) 77 (69.4) 16 (76.2) 14 (63.6)
 I used to smoke cigarettes 33 (21.0) 19 (17.1) 3 (14.3) 4 (18.2)
Alcohol beverages/week (mean (SD)) 5.52 (6.22) 5.51 (6.26) 3.86 (4.29) 4.23 (6.55) 0.376
Anxiety and/or depression (%) 87 (55.4) 46 (41.4) 14 (66.7) 13 (59.1) 0.048
Dyslipidemia (%) 38 (24.2) 28 (25.2) 1 (4.8) 6 (27.3) 0.212
Chronic kidney disease (%) 1 (0.6) 2 (1.8) 0 (0.0) 0 (0.0) 0.703
Diabetes (%) 3 (1.9) 9 (8.1) 2 (9.5) 4 (18.2) 0.007
Other chronic comorbidity (%) 57 (36.3) 46 (41.4) 7 (33.3) 11 (50.0) 0.540
Family history of heart disease or stroke (%) 48 (30.6) 49 (44.1) 6 (28.6) 10 (45.5) 0.089
Self-perceived health status (%) 0.133
 Excellent 6 (3.8) 1 (0.9) 0 (0.0) 0 (0.0)
 Very good or good 79 (50.3) 59 (53.2) 6 (28.6) 9 (42.9)
 Fair 52 (33.1) 40 (36.0) 13 (61.9) 6 (28.6)
 Poor or no response 20 (12.7) 11 (9.9) 2 (9.5) 6 (28.6)
Financial status: inadequate income (%) 130 (82.8) 81 (73.0) 17 (81.0) 15 (68.2) 0.164
Godin-Shephard Physical Activity, Insufficiently active (%) 80 (51.0) 56 (50.5) 14 (66.7) 12 (54.5) 0.564
Sodium intake (mg/day) (mean (SD)) 3897.25 (2067.46) 3384.44 (1436.45) 3002.62 (973.85) 3083.73 (1512.78) 0.042

Comparisons of nominal categorical variables were made using chi-square tests; continuous variables and categorical variables with a natural ordering (highest level of education and self-perceived health status) were tested using Kruskal-Wallis tests. Bold values are significant at the alpha = 0.05 level

Percent is calculated using the denominator at the top of each column

P-values show overall associations between medication category and each characteristic