Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Nov 9;11:2181–2198. doi: 10.2147/JHC.S479463

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 Priyanka et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

2,2’-Bipy derivatives NPS (1–6) inhibited the viability and proliferation of HepG2 cell lines. (A) Effects of various doses of the derivatives NPS (1–6) on the cell viability of HepG2 cells. The total percentage of cells was measured using an MTT assay. A dose-dependent decrease was observed in cell viability after treatment at 48 h; (B) Effects of the derivatives NPS (1–6) at three doses 0.5 × IC₅₀, IC_50, and 2 × IC₅₀ on the cell proliferation of HepG2 cells by colony formation assay using crystal violet dye. A dose-dependent decrease in colony numbers appears with an increase in concentration. (C) Colony formation capacity of HepG2 cells after treatment with the derivatives. The asterisks shown are significant when calculated for their colony formation capacity when compared to the control. The data from three independent experiments were presented as mean ± SD, with statistical differences indicated compared to the control group. The p-value ≤ 0.0001 (****) indicates significance.