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. 2024 Sep 19:15910199241285157. Online ahead of print. doi: 10.1177/15910199241285157

Table 1.

Overview of included studies.

Study ID Country Study Duration Study design Patients N (intervention/control) Bridging Intravenous thrombolysis, N (%) ASPECTS, Median (Range) Main inclusion criteria
Wu et al., 2018 China 2015–2017 Single-center Prospective Study 45/68 50 (44.2) Intervention 8 (7–10)
Control: 9 (8–10)
1) LVO within 6 h from onset
2) NIHSS ≥6
3) Occlusion in M1
Wan et al., 2023 China 2019–2022 Single-center Randomized Trial 71/71 0 (0) NR 1) LVO within 24 h from onset
2) NIHSS ≥6
3) Occlusion in M1, M2, ICA
Chen et al., 2016 China 2013–2014 Single-center Retrospective Study 26/- NR Intervention: 6 (6–9) 1) LVO within 8 h from onset
2) NIHSS ≥8
3) Occlusion in M1, M2, ICA, BA, VA
Li et al., 2023 China 2020–2022 Single-center Single-arm Prospective Study 20/20 NR Intervention 8.4 (1.05) *
Control: 8.4 (0.83) *
1) LVO achieving TICI 2b
Tian et al., 2023 China 2018–2022 Single-center Prospective Study 62/80 29 (20.4) NR 1) Within 24 h from onset
2) NIHSS ≥6
3) Occlusion in M1

NR indicates Not reported; ASPECTS, Alberta stroke program early computerized tomography score; LVO, Large vessel occlusion; NIHSS, National institutes of health stroke scale; M1, First segment of the middle cererbral artery; M2, Second segment of the middle cererbral artery; ICA, Internal caratoid artery; BA, Basilar artery; VA, Vertebral artery; TICI, Thrombolysis in cerebral infarction.

* Data is described as mean (standard deviation).