Table 3.
Reference | Cutoff (µg/mL) | OR (95%CI) | Specificity | Sensitivity | PPV | NPV | Accuracy | AUC |
---|---|---|---|---|---|---|---|---|
Successful recanalization | ||||||||
Ohbuchi et al. | 6.7 | 5.51 (1.80–16.88) | 36% | 91% | 79% | 60% | 76% | - |
First-pass effect | ||||||||
Xie and Tang | 0.97 | 0.81 (0.52–0.96) | 79% | 79.30% | - | 87% | - | 0.761 |
Baek et al. | 1.09 | 0.92 (0.85–0.98)/500 ng/mL | 47.90% | 76.10% | - | - | - | 0.631 |
Reocclusion | ||||||||
Li W. et al. | - | 1.06 (1.01–1.12) | - | - | - | - | - | - |
Favorable outcome | ||||||||
Baek et al. | 0.67 | 0.88 (0.81–0.97) per 500 ng/mL | 70.30% | 67% | - | - | - | 0.722 |
Li J. et al. | - | 1.14 (1.04–1.26) | - | - | - | - | - | - |
Ohbuchi et al. | 1.9 | 3.86 (1.27–11.75) | 62% | 64% | 45% | 78% | 63% | - |
Hisamitus et al. | 1.9 | 1.27 (1.0–1.6) | 80% | 60.60% | - | - | - | - |
Lee et al. | - | 1.524 (1.043–2.226)* | - | - | - | - | - | - |
Low DVT | ||||||||
Han et al. | 1.62 | 1.350 (1.150–1.585) | 70.20% | 71.60% | - | - | - | 0.749 |
sICH | ||||||||
Qiu et al. | 2.27 | 2.45 (1.75–3.43) | 86.20% | 64.60% | - | 94.60% | - | 0.774 |
OR: odds ratio; CI: confidence interval; PPV and NPV: positive and negative predictive values; AUC: area under the curve.
*Association with unfavorable functional outcome; - Outcome was not reported by this study.