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. 2024 Nov 13;19(11):e0313789. doi: 10.1371/journal.pone.0313789

Table 1. Participants’ characteristics.

EA group AC group Control group p-value
(N = 24) (N = 24) (N = 24)
Demographic characteristics
Age (years) 35.3 ± 12.0 38.3 ± 13.9 42.2 ± 12.2 0.274
Height (cm) 160.0 ± 5.37 158.0 ± 6.79 159.0 ± 4.98 0.900
Weight (kg) 54.5 ± 8.57 54.0 ± 5.77 51.5 ± 5.29 0.189
BMI (kg/m2) 21.3 ± 2.89 21.5 ± 1.66 20.4 ± 2.18 0.135
Exercise (%) 62.5 79.2 54.2 0.180
Smoking (%) 0 4.2 0 0.391
Alcohol (%) 29.2 33.3 25.0 0.817
Clinical characteristics
Hand VAS score (T0) 5.83 ± 1.05 6.21 ± 1.38 7.08 ± 1.25 0.003
Hand VAS score (T1) 4.08 ± 1.67 4.33 ± 1.63 6.75 ± 1.39 <0.001
Hand VAS score (T2) 4.42 ± 1.84 4.71 ± 2.10 6.13 ± 1.68 0.005
Feet VAS score (T0) 6.79 ± 1.02 7.17 ± 1.40 7.46 ± 1.14 0.163
Feet VAS score (T1) 5.00 ± 1.82 5.67 ± 1.79 7.13 ± 1.36 <0.001
Feet VAS score (T2) 4.50 ± 1.69 5.29 ± 2.10 6.46 ± 1.61 0.002
ΔT hands (°C) (T0) 1.56 ± 1.42 1.25 ± 1.26 2.30 ± 1.98 0.068
ΔT hands (°C) (T1) 0.70 ± 1.49 0.67 ± 1.97 1.51 ± 2.80 0.319
ΔT hands (°C) (T2) 0.38 ± 2.17 0.90 ± 1.81 1.34 ± 2.36 0.299
ΔT feet (°C) (T0) 2.31 ± 2.41 2.99 ± 1.58 2.54 ± 1.95 0.489
ΔT feet (°C) (T1) 2.72 ± 2.26 2.25 ± 2.30 2.34 ± 2.16 0.745
ΔT feet (°C) (T2) 0.84 ± 1.75 2.38 ± 1.74 2.22 ± 2.11 0.011
WHOQOL-BREF
Total score (T0)
79.33 ± 7.84 78.75 ± 9.03 75.96 ± 8.46 0.341
WHOQOL-BREF
Total score (T1)
88.83 ± 8.81 87.29 ± 10.82 82.83 ± 9.16 0.089
WHOQOL-BREF
Total score (T2)
91.00 ± 10.84 86.96 ± 10.83 81.21 ± 11.10 0.011
WHOQOL-BREF
Physical domain (T0)
23.67 ± 2.96 23.63 ± 3.03 22.67 ± 3.25 0.450
WHOQOL-BREF
Physical domain (T1)
24.50 ± 3.22 24.54 ± 3.31 23.17 ± 3.17 0.252
WHOQOL-BREF
Physical domain (T2)
25.54 ± 3.71 24.21 ± 3.19 22.63 ± 3.99 0.026
WHOQOL-BREF
Psychological domain (T0)
18.92 ± 2.99 19.00 ± 3.11 18.50 ± 2.62 0.817
WHOQOL-BREF
Psychological domain (T1)
19.83 ± 2.82 19.46 ± 2.75 18.46 ± 2.34 0.185
WHOQOL-BREF
Psychological domain (T2)
20.75 ± 2.92 19.33 ± 2.82 22.63 ± 3.99 0.015
WHOQOL-BREF
Social domain (T0)
10.54 ± 1.25 10.08 ± 1.59 10.21 ± 1.28 0.497
WHOQOL-BREF
Social domain (T1)
10.33 ± 1.09 10.33 ± 1.49 10.21 ± 1.47 0.935
WHOQOL-BREF
Social domain (T2)
10.42 ± 1.50 10.13 ± 1.62 10.04 ± 1.33 0.660
WHOQOL-BREF
Environmental domain (T0)
26.21 ± 3.12 26.04 ± 3.26 24.58 ± 2.99 0.148
WHOQOL-BREF
Environmental domain (T1)
27.42 ± 3.28 26.21 ± 3.95 24.63 ± 2.89 0.021
WHOQOL-BREF
Environmental domain (T2)
27.54 ± 3.79 26.42 ± 4.05 23.83 ± 3.37 0.003

EA, electroacupuncture; AC, acupuncture; VAS, visual analog scale; BMI, body mass index; WHOQOL-BREF, World Health Organization Quality of Life-BREF