TABLE 2.

Frequency of LKB1 deep deletion co-occurring with common mutations in HGSOC. Analysis of 311 ovarian cancer serous cystadenocarcinoma in TCGA dataset via http://www.cbioportal.org (access date 27th September 2024). Statistical analysis was performed using Fisher’s exact test.

Mutant gene	Number of patients	Number of patients with LKB1 co-mutations	% Occurrence of LKB1 co-mutation	p-value	95% CI	Odds ratio
CCNE1	67	6	8.96	0.12	0.66, 7.29	2.29
RB1	39	2	5.13	1	0.11, 4.62	1
TP53	275	14	5.09	1	0.20, 8.61	0.91
PTEN	21	1	4.76	1	0.02, 6.59	0.92
MYC	128	5	3.91	0.45	0.17, 2.05	0.64
NF1	37	1	2.70	0.70	0.01, 3.31	0.48
BRCA1	20	0	0	0.61	0.00, 3.89	0
BRCA2	22	0	0	0.61	0.00, 3.49	0