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. 2024 Oct 31;14:1436587. doi: 10.3389/fonc.2024.1436587

Table 3.

Patient follow up during the last year of life.

N=100
Localization at death
 Home
 Local hospital
 Geriatrics
 Palliative care
 Hematology/specialized department
 ICU

20
8
12
20
25
15
Time between last treatment and death (days) 38 (1-2443)
Number of imagery exams during last year 7 (0-25)
Treatment received during last year
Steroids and palliative
Anticoagulants/antiagregants
Antiinfectious (preventive)
Biphosphonates
Growth factors
RBC transfusions
Platelet transfusions
IMIDs
Proteasome inhibitors
Melphalan
High dose Mel with ASCT
Anti CD38
Clinical trial
Anti-infectious (curative)
Painkillers

92
68
74
31
44
52
31
71
54
2
1
44
5
49
66
Response to last therapy
CR/VGPR
PR
SD
PD
Non evaluable

5
7
8
75
5
Disease status at death
 Remission/stable
 Progressive
 Unknown

18
77
5
Biology at time of death
 Hypercalcemia > 2.5 mM
 Anemia (Hb<90g/L)
 Renal failure (creat >110)
 Neutropenia
 Lymphopenia < 1 giga/L
 Thrombocytopenia < 50 giga/L

24
52
49
17
73
40
Immediate cause of death£
 Myeloma progression
 Other disease, including:
  Other neoplasia
  Neurological diseases
 Infection
 DVT
 Treatment related toxicity

78
23
7
4
36 (including 4 Covid)
3
32

CR, complete response; DVT, deep vein thrombosis; PR, partial response; SD, stable disease; VGPR, very good partial response; ICU, intensive care unit; RBC, red blood cell; IMID, immunomodulatory drugs; Mel, Melphalan. £: the total value of causes exceeds 100 as several causes were deemed involved in occurrence of death in certain patients.