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. 2024 Sep 12;271(11):7250–7263. doi: 10.1007/s00415-024-12608-6

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© The Author(s) 2024

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Fig. 2 — Manhattan plot. The Manhattan plot of − log₁₀(p) of associations from fixed-effect meta-analysis. The genome-wide significance level is set at p = 5 × 10^–8 (blue line), whereas suggestive significance threshold at p = 5 × 10^–5 (red line). rsIDs of the top five associated SNPs are marked