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. 2024 Oct 24;271(11):7156–7168. doi: 10.1007/s00415-024-12604-w

Fig. 4.

Fig. 4

Neural recordings from the first human user of a microelectrode array based neuroprosthetic (a) A well-isolated single unit recording from a single electrode (trace shows the superposition of 80 waveforms); (b) Over 80 seconds the participant was asked to imagine performing a series of movements in the arm contralateral to the array. Spiking activity of a recorded unit is shown along the top of the panel with the normalised integrated firing rate immediately below that. This unit demonstrates an increased firing frequency with the instruction to move hands apart/together; (c) Spike rates for two units recorded simultaneously during the performance of movement of the on screen neural cursor. The unit recorded in channel 1 demonstrates increased firing with the cue to move the cursor upwards but not downwards. Conversely, the unit recorded in channel 2 demonstrates increased firing following the cue to move the cursor downwards but not upwards; (d) Research technician and participant neural cursor traces during a 5 second period of the participant tracking the cursor; Panel figures adapted from [14] and used with permission. Channel numbers altered for simplicity of presentation

Figure adapted from source referenced and images reproduced with permission