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. 2024 Nov 13;14:27883. doi: 10.1038/s41598-024-77633-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 4 — Visualization of the effectiveness of RN and RAIN for VS (red) and cochleas (sky-blue) according to different normalization configurations of TANQ; (a) real ${ceT}_{1}$ images, (b)-(d) pseudo- ${hrT}_{2}$ images from ${ceT}_{1}$ images generated by TANQ with different normalization configurations, and (e) real ${hrT}_{2}$ images. In the real ${ceT}_{1}$ images, the intensity of the VS is higher than that of other tissues due to the contrast agent, while the VS in the real ${hrT}_{2}$ images shows similar intensity to other tissues. Conversely, the cochlea exhibits very low intensity in real ${ceT}_{1}$ images (a), whereas it appears relatively distinct in real ${hrT}_{2}$ images (e).