Table 2.
Descriptive statistics on measures of ADHD, cardiometabolic diseases and biomarkers.
| ADHD, cardiometabolic diseases and biomarkers | Sample size | Prevalence (%) |
|---|---|---|
| ADHD | 50,768 | 383 (0.82) |
| Metabolic disease | 50,768 | 14,133 (30.38) |
| Type 2 diabetes | 50,768 | 1345 (2.66) |
| Obesity | 50,768 | 6685 (13.21) |
| Hypertension | 50,768 | 9621 (20.53) |
| Cardiovascular disease | 50,768 | 2450 (5.19) |
| Thrombosis | 50,768 | 598 (1.27) |
| History of coronary artery bypass grafting | 50,768 | 658 (1.39) |
| Myocardial infarction | 50,768 | 449 (0.95) |
| Atherosclerosis | 50,768 | 226 (0.48) |
| Stroke | 50,768 | 344 (0.73) |
| Narrowing carotid arteries | 50,768 | 115 (0.24) |
| Heart failure | 50,768 | 242 (0.51) |
| Atrial fibrillation | 50,768 | 242 (0.51) |
| Heart valve disorders | 50,768 | 492 (1.04) |
| Aneurysm | 50,768 | 130 (0.28) |
| Cardiometabolic biomarker | Sample size | Mean (Standard deviation) |
| Glucose metabolic | ||
| Glucose (mmol/L) | 43,424 | 4.96 (0.73) |
| HbA1c (%) | 43,411 | 5.49 (0.32) |
| Red blood cells | ||
| Haematocrit (v/v) | 46,985 | 0.42 (0.03) |
| Haemoglobin (mmol/L) | 46,969 | 8.76 (0.76) |
| Lipid metabolism | ||
| Total cholesterol (mmol/L) | 47,052 | 5.09 (1.02) |
| LDL cholesterol (mmol/L) | 47,055 | 3.25 (0.93) |
| HDL cholesterol (mmol/L) | 47,039 | 1.47 (0.37) |
| Triglycerides (mmol/L) | 46,723 | 1.11 (0.57) |
| Apolipo A1 in serum (g/L) | 5245 | 1.61 (0.27) |
| Apolipo B100 (g/L) | 5248 | 0.93 (0.24) |
| Liver function | ||
| ALT (U/L) | 23,750 | 22.18 (11.26) |
| AST (U/L) | 23,790 | 23.88 (6.33) |
| Alkaline Phosphatase (U/L) | 23,884 | 62.15 (16.71) |
| Gamma-GT (U/L) | 23,734 | 24.44 (14.77) |
| Kidney function | ||
| Creatinine (µmol/L) | 46,997 | 73.29 (12.14) |
| Creatinine 24 h urine (mmol/L) | 46,834 | 8.09 (3.74) |
| Estimated Glomerular Filtration Rate (eGFR) | 47,088 | 99.85 (15.21) |
| Urinary albumin excretion (UAE) 24 h | 23,902 | 11.53 (100.87) |
| Urinary albumin-creatinine ratio (UACR) | 23,022 | 5.07 (47.02) |
| Uric acid (mmol/L) | 58,470 | 0.29 (0.07) |
| Thyroid | ||
| Free T3 (pmol/L) | 13,875 | 5.22 (0.62) |
| Free T4 (pmol/L) | 13,887 | 15.74 (2.05) |
| TSH (mU/L) | 13,798 | 2.45 (1.51) |
| Inflammation | ||
| hsCRP (mg/L) | 22,781 | 2.90 (2.90) |
| Leucocytes (109/L) | 46,872 | 5.98 (1.50) |
| Blood pressure | ||
| Systolic BP | 46,711 | 126.59 (16.56) |
| Diastolic BP | 46,760 | 74.27 (10.08) |
Sample size = Genotyped individuals with measured questionnaire or lab-based data. Values ± >4 SDs are excluded.
BP blood pressure, hsCRP high-sensitivity C-reactive protein, TSH Thyroid stimulating hormone, Free T4 free thyroxine, Free T3 free triiodothyronine, Apolipo Apolipoprotein, Gamma-GT Gamma-glutamyl transferase, AST Aspartate aminotransferase, ALT Alanine transaminase, HDL high-density lipoprotein, LDL low-density lipoprotein, HbA1c Haemoglobin A1c.